Ziyi Yang (杨子毅)

Ziyi Yang (杨子毅)

Ph.D. candidate in Organic Chemistry at Tsinghua University, combining computational protein design, generative models, and chemical protein synthesis to build beyond-biology proteins.

Cross-Chirality Generalization by Axial Vectors for Hetero-Chiral Protein-Peptide Interaction Design

Published in ICML, 2026

This work introduces chirality-aware geometric features for generative design of D-peptide binders targeting L-proteins.

Recommended citation: Z. Yang, Z. Tian, Y. Jia, T. Zhang, J. Zheng, H. Wang, Y. Su, J. He, L. Liu, and Y. Lan. (2026). "Cross-Chirality Generalization by Axial Vectors for Hetero-Chiral Protein-Peptide Interaction Design." ICML.
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